Introduction to Workshop
Welcome to the International workshop on "AI-Driven Multimodal Approaches for Brain Disease Diagnosis and Treatment" to be held in Wuhan, China, from 15 to 18 December 2025, in conjunction with the IEEE International Conference on Bioinformatics and Biomedicine (BIBM).
This workshop aims to explore cutting-edge AI and deep learning methods for analyzing multimodal health data (e.g., genomics, proteomics, metagenomics, imaging, EEG, and/or electronic health records) to improve the diagnosis, monitoring, and treatment of brain diseases. The workshop will bring together researchers and practitioners to discuss challenges, share innovations, and foster collaborations in computational biomedicine.
We invite you to submit papers with unpublished, original research describing recent advances on the areas related to this workshop. All papers will undergo peer review by the conference program committee. All accepted papers will be included in the main conference proceedings which are published in the IEEE digital library, indexed in Google Scholar and Scopus.
Research Topics Included in the Workshop
Topics of interest include, but are not limited to:
- AI and Machine Learning Applications: Deep learning models for early diagnosis of neurological and psychiatric disorders.
- Multi-Omics Integration: Combining genomics, transcriptomics, and proteomics for biomarker discovery.
- Multimodal Data Fusion: Integration of genomics, transcriptomics, proteomics, neuroimaging, and clinical records for personalized medicine.
- AI Drug Study: Deep learning models for predicting drug responses and side effects, and may help to improve the treatments for the brain, neural, or mental disorders.
- Clinical Decision Support Systems: AI tools for real-time diagnosis and treatment recommendations and planning.
- Translational Applications: studies of AI models deployed in clinical settings, such as Federated learning and privacy-preserving computation in brain health research.
Invited Speakers (Confirmed)
We are honored to welcome the following distinguished speakers:
-
Prof. Dong Xu
Affiliation: University of Missouri
Talk Title: Applications of AI Foundation Models for Biomedical Research -
Prof. Haixia Long
Affiliation: Hainan Normal University
Talk Title: Multi-omics data analysis based on deep learning and high-order networks -
Prof. Jianing Qiu
Affiliation: Mohamed bin Zayed University of Artificial Intelligence
Talk Title: Medical Al: From Foundation Models, Al Agents to Human-Al Collaboration -
Prof. Zhe Liu
Affiliation: East China University of Science and Technology
Talk Title: AI-Driven Interpretation of Mutation-Induced PPI Perturbations in Brain Diseases -
Prof. Xiaoyue Feng
Affiliation: Jilin University
Talk Title: From Images to Insights: Building Next-Generation Computational Microscopy for Spatial Omics -
Prof. Xianfang Wang
Affiliation: Henan Institute of technology
Talk Title: AttentionMol:Multi-Head Attention for Pan-Cancer Targeted Molecule Design -
Prof. Wenji Ma
Affiliation: Shanghai Jiao Tong University
Talk Title: Prior knowledge guided multi-omics data analysis. -
Prof. Hao Zhang
Affiliation: Jilin University
Talk Title: AI-Driven Multi-scale Biological Modeling: RNA Structures, Plant-Fungal Interactions, and Spatial Omics -
Prof. Weidi Wang
Affiliation: Shanghai Mental Health Center
Talk Title: Decoding of neurodevelopmental trajectories: from infant-critical genes to early diagnosis and intervention for brain disorders
Important Dates (USA Eastern Standard Time)
- Oct 15, 2025: Due date for full workshop paper submissions
- Nov 10, 2025: Notification of paper acceptance to authors
- Nov 23, 2025: Camera-ready submission of accepted papers
- Dec 15-18, 2025: Workshop held in conjunction with IEEE BIBM 2025
Program Chairs / Co-Chairs
Dr. Guan Ning Lin
Shanghai Jiao Tong University
Dr. Han Wang
Northeast Normal University
Program Committee Members
- Dr. Dong Xu (University of Missouri – Columbia)
- Hao Zhang (College of Computer Science and Technology, Jilin University)
- Wang-Ren Qiu (Jingdezhen Ceramic University)
- Hao Lin (University of Electronic Science)
- Xiao-Hu Shi (Jilin University)
- Xiao-Yue Feng (Jilin University)
- You Zhou (Jilin University)
- Wen-Ji Ma (Shanghai Jiao Tong University School of Medicine)
- Zhe Liu (East China University of Science and Technology)
Paper Submission
- We call for original and unpublished research contributions to the workshop.
- We accept submission of Full paper (6 - 8 pages IEEE 2-column format), through the online submission system (you can download the format instruction here). Electronic submissions in PDF format are required.
- Online submission system is at submission site. (Please be sure to select our workshop listed as "ProW227: AI-Driven Multimodal Approaches for Brain Disease Diagnosis and Treatment" for submission).
Workshop Schedules (Room: New York, Wanda Reign Wuhan 2F)
| Paper ID | Title | Authors | Time |
|---|---|---|---|
| Invited Talk | Applications of AI Foundation Models for Biomedical Research |
Prof. Dong Xu (University of Missouri) |
08:30 - 09:10 |
| Invited Talk | AI-Driven Multi-scale Biological Modeling: RNA Structures, Plant-Fungal Interactions, and Spatial Omics | Prof. Hao Zhang | 09:10 - 09:30 |
| Invited Talk | AttentionMol:Multi-Head Attention for Pan-Cancer Targeted Molecule Design | Prof. Xianfang Wang | 09:30 - 09:50 |
| Invited Talk | From Images to Insights: Building Next-Generation Computational Microscopy for Spatial Omics | Prof. Xiaoyue Feng | 09:50 - 10:10 |
| Invited Talk | Multi-omics data analysis based on deep learning and high-order networks | Prof. Haixia Long | 10:10 - 10:30 |
| 10:30 - 10:40 — Tea Break — | |||
| Invited Talk | Medical Al: From Foundation Models, Al Agents to Human-Al Collaboration | Prof. Jianing Qiu | 10:40 - 11:00 |
| Invited Talk | Prior knowledge guided multi-omics data analysis | Prof. Wenji Ma | 11:00 - 11:20 |
| Invited Talk | Decoding of neurodevelopmental trajectories: from infant-critical genes to early diagnosis and intervention for brain disorders |
Dr. Weidi Wang (Shanghai Mental Health Center) |
11:20 - 11:40 |
| Invited Talk | AI-Driven Interpretation of Mutation-Induced PPI Perturbations in Brain Diseases | Prof. Zhe Liu | 11:40 - 12:00 |
| 12:00 - 14:00 — Lunch Break — | |||
| S23204 | MoCA-Dialog: A Benchmark for Fine-Grained Evaluation of Large Language Models in Clinical Cognitive Assessment Dialogues | Yunjia Zhang, Junyi Zhu, Rui Wang, Tianai Zhuang, Jinqiu Sang, and HA KYUNG KIM | 14:00 - 14:18 |
| B533 | Enhancing Dual-Stream Attention Network: A Novel Multimodal Fusion Approach for Cognitive Assessment in Cerebral Small Vessel Disease | Sen Zeng, Hong Zhou, Yang Liu, Bowen Ji, Jiaqi Huang, Haitao Yang, Chenying Lu, Jiansong Ji, and Peiwu Qin | 14:18 - 14:36 |
| B630 | DuST-Net: Dual-Stream Temporal Network for Early Alzheimer's Screening from Hierarchical Speech-Language Features | Chen Qian, Yi Chen, Jialong Wang, Jiyun Li, Jiabao Zhao, and Ying Liu | 14:36 - 14:54 |
| B776 | Cross-modal contrastive learning for mapping addiction-related brain circuits in multi-parametric MRI | Lehao Wang, Jinze Du, Wenhua Lin, Yi Lu, Huawei Wang, and Kunhua Wang | 14:54 - 15:12 |
| B818 | Machine Learning Framework for Non-Invasive Drug Abuse Detection Using Pupillary Light Reflex Dynamics | Jie Shen, Jinze Du, Bo Ye, Jia Lv, Tao Wan, and Kunhua Wang | 15:12 - 15:30 |
| B1100 | CoLA-DTA: Cross-modal Latent Alignment for Generalization-Enhanced Drug–Target Affinity Prediction | Li Zhang, Chen Cui, Xike Ouyang, Xinying Wang, and Han Wang | 15:30 - 15:48 |
| B1502 | PGAD: Prototype-Guided Adaptive Distillation for Multi-Modal Learning in AD Diagnosis | Yanfei Li, Jingyu Liu, Xi Wang, KaiYang Zhao, and Haixian Zhang | 15:48 - 16:06 |
| 16:06 - 16:24 — Tea Break — | |||
| B1711 | Modality-Guided Edge Fusion and Semantic Enhancement for Multi-Modal Brain Tumor Segmentation | Wentong Zhou, Yuwen Zeng, Xiaoyong Zhang, Ruili Li, Arata Nagai, Masayuki Kanamori, Hidenori Endo, Kuniyasu Niizuma, and Noriyasu Homma | 16:24 - 16:42 |
| B2023 | Seg4Fusion: A Tumor-Aware Framework for 3D Medical Image Fusion | Haiyu Song, Jiawei Feng, Maoyu Wang, Wenqi Wang, Aohua Ma, and Zeyu Wang | 16:42 - 17:00 |
We will continue to update the workshop information, including the list of program committee members and the confirmed keynote speaker, as they become available. We look forward to receiving your submissions and to a fruitful and enlightening workshop at the IEEE BIBM 2025 Conference!